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cerevisiae , which has become a popular model for fungal development biology ( The first step of the purine pathway for riboflavin biosynthesis begins in a similar manner in all microorganisms, from the conversion of GTP into 2,5-diamino-6-ribosyl-amino-4(3H)pyrimidinedione 5-phosphate (DARPP), formate, and pyrophosphate catalyzed by GTP cyclohydrolase II ( RIB1 in A