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16 Treatment may also decrease the risk for mortality and acute myocardial infarction among patients with lupus nephritis, as well as reduce the progression of chronic kidney disease
We uncover known pathways, such as DAF-16 in mediating the extended lifespan of the glp-1(-) and fem-3(-) mutants, and also reveal additional insights, including a possible central role of sphingolipid metabolism in the longevity of self-sterile mutants and that masculinized mutants may serve as a useful genetic model for further investigation of mating-induced metabolic reprogramming and premature death (Fig
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CNS-linked peptide pathway mapping and neuromodulatory behavior
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