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Manufacturing and API Supply as Strategic Barriers The sheer complexity of manufacturing GLP-1 and GIP peptides at a global scale serves as a practical, non-legal barrier to competition

Despite being discovered first, it received less clinical attention for decades because early research suggested that GIP signaling was impaired in type 2 diabetes, making it seem like an unlikely therapeutic target

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Ketogenic diets alter the gut microbiome resulting in decreased intestinal Th17 cells

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