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Insulin and insulin analogs: cancer risk assessment As one of the most effective anti-diabetic therapies currently available, insulin therapy for glycemic control carries risks of hypoglycemia and weight gain

The clinical expert highlighted the following outcomes that are important when assessing whether a patient is responding to treatment in clinical practice: improvement in glycemic parameters, improvement in body weight with the attendant improvement in blood pressure and lipids, and long-range improvement in microvascular and macrovascular events, in addition to improvement in quality of life

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It could also cause adverse effects

Scientific References: Le Roith D, Bondy C, Yakar S, Liu JL, Butler A., Endocrine Reviews , 2001