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Promotes hyperplasia (creation of new muscle fibers) Accelerates muscle repair and recovery post-exercise Enhances nutrient transport and cellular growth signaling IGF1 induces proliferation and differentiation of muscle satellite cells, enabling hypertrophic adaptations in response to overload. Adams et al., Journal of Applied Physiology Muscle Preservation Post-Cycle IGF1 LR3 helps preserve lean mass during post-cycle therapy (PCT) or caloric restriction
In HEI-OC1 cells, overexpression of miR-34a resulted in autophagy flux impairment and cell activity suppression, which could be counteracted by miR-34a inhibition
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