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A variant in the GLP1R gene is associated with differences in weight loss, while a variant in the GIPR gene predicts nausea specifically in people taking tirzepatide (Mounjaro), not semaglutide (Wegovy or Ozempic)
Symptoms of GLP-1 Medication Intolerance The most common symptoms involve the digestive system
Some people find that GI effects from alcohol improve after several months on stable doses, but others continue to experience increased sensitivity to alcohol throughout treatment
Eating smaller meals, keeping fat moderate, increasing fiber, and staying hydrated can help reduce nausea, reflux, and other digestive side effects
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