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374 PROTACs targeting the N-terminal domain (NTD) of AR degrade AR variants, effectively blocking persistent AR signaling and overcoming anti-androgen resistance in advanced prostate cancer
Single-cell genomics to understand disease pathogenesis
Prospective studies involving pregnant and lactating females should be performed to assess the long-term effects of SSRIs on fetal and neonatal development
Understanding the difference saves you from abandoning an effective ingredient prematurely
Adjust dose to maintain IGF-1 within target range Annual: thorough labs plus assessment of continued need for therapy IGF-1 levels above the upper limit of normal warrant dose reduction
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