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Because semaglutide slows digestion, lying flat can cause stomach acid to move into the esophagus and irritate the throat, triggering a cough

Among 17,604 participants with established cardiovascular disease and overweight or obesity but without diabetes, the primary event hazard ratio was 0.80 (95% CI 0.72-0.90) over a mean 39.8-month follow-up

So it's really a way of doing a beautifully randomized controlled trial with an observational study because you're not biased

Presented for research literature review only Naidu GS et al

However, there was quick backlash from Wegovy manufacturer Novo Nordisk, who said it would sue Hims & Hers, claiming the pills are an unapproved knockoff amongst other patient concerns