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NHS guidance is clear that it should be prescribed and given by, or under the supervision of, a suitably qualified professional
In humans, B12 deficiencies are seen more commonly in people consuming a vegetarian or vegan diet who are not supplementing enough B12
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Much of the supporting research summarized in peer-reviewed literature relies on animal studies, such as GLP-1 receptor-knockout mice and rodent injection trials, rather than large-scale human trials, and peptide-based drugs overall are described as rarely used in real-world patient care because of lingering questions about safety, effectiveness, and inadequate insurance coverage
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