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Cochrane Database Syst Rev 6:CD008684 Maeda J, Kijima A, Inoue K, Ishii Y, Ichimura R, Takasu S, Kuroda K, Matsushita K, Kodama Y, Saito N et al (2014) In vivo genotoxicity of Ginkgo biloba extract in gpt delta mice and constitutive androstane receptor knockout mice
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Moreover, meta-analyses of observational studies have reported that circulating concentrations of vitamin E were significantly lower in AD patients than in cognitively healthy individuals (104, 105)
Glutathione is widely known as the master antioxidant because of its central role in protecting cells from oxidative stress
While direct human trials on the combination for cognition are sparse, the mechanistic synergy supports potential for addressing mitochondrial dysfunction in age-related cognitive decline [5]
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