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Monitoring allows detection of unexpected hepatic or renal effects that have not been characterized in formal human trials
It has also been used to treat premature ejaculation, chronic depression, pancreatitis, Parkinsons disease, and AIDS myelopathy
What can shorten the usable window The 28-day rule does not remove the need for inspection
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Both pairs are consistent with the borrowed exponent, but neither is a clean test: in both, the lighter arm is also the higher-starting-dose arm, so body weight and titration path are collinear and the comparison cannot separate them
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