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Third, extend models to thermoneutral large-rodent settings with metabolic and cardiovascular telemetry to expand safety margins
A serum B12 level test and, ideally, a methylmalonic acid (MMA) test should precede any B12 injection recommendation
9 The researchers also noted that sublingual B12 has many practical advantages over injections, which are painful, costly, and require repeated clinic visits
[5] This creates a more complex interpretive problem because several pathways may be involved at once, and the order of causality is not always clear
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