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The weight-independent insulin sensitization may suggest treatment durability in contrast to treatments that provide only weight-dependent effects
In the evolving landscape of diabetes and obesity treatment, two medicationsTirzepatide and Retatrutide, are generating considerable attention
However, patients require closer monitoring of hydration status, blood pressure, and renal function, as the combination may increase dehydration risk, particularly during gastrointestinal side effects or dose escalation periods
Stucky, Real-World Temporal and Indication-Specific Variation in Drivers of GLP-1 RA Discontinuation (Value in Health, 2025
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