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MOTS-c is a short peptide (16 amino acids), which makes it relatively resistant to the enzymatic degradation that degrades larger peptides, but also means that reconstitution technique and storage conditions matter considerably
As an example, the Amgen drug MariTide is showing impressive results in trials
In addition, the risk of composite major adverse limb events in the GLP-1RA group was borderline significantly lower than that in the DPP-4i group (Fig
At that rate, shelf life is rarely an issue because you finish the vial long before the BUD
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