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Taken together, these efficacy and safety observations suggest that, for older patients without CV disease with T2DM who are not at A1C target despite metformin monotherapy, it is reasonable to preferentially recommend a DPP-4 inhibitor rather than an SGLT2 inhibitor as add-on therapy

Blots were developed with SuperSignal West Femto Maximum Sensitivity Substrate (Thermo Scientific)

Food Choices to Increase GLP-1 The nutrients that help stimulate GLP-1 secretion are typically found in healthy foods included in dietary guidelines

18.2% of TRIUMPH-4 participants on the 12 mg retatrutide dose discontinued due to adverse events, compared to 4% on placebo

Not using GLP-1 during breastfeeding doesnt mean putting your health on hold