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AOD 9604 is known for helping with weight management and metabolism
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The compound modulates neuronal activity in the lateral hypothalamus, specifically silencing GABAergic neurons that promote feeding behavior, thereby reducing the drive to consume food while enhancing satiety responses
Whether this observation is solely the consequence of translocation of Parasutterella bacteria from the intestine to the EWAT or driven by more indirect mechanisms such as bacterially-produced metabolites 85 is yet to be determined
doi:10.1016/j.drudis.2021.07.009
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