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Our research group investigated several ligands of BBB nutrient transport systems and the combination of the amino acid alanine and among them the tripeptide glutathione (A-GSH) was the most successful for targeting the BBB in case of nanovesicles [32, 33] or 3-armed poly(l-glutamic acid) (3-PLG) nanocarriers in BBB cultures and animals [24]
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doi: 10.1016/j.livsci.2009.07.002 110 WuS.-T.YuS.-T.LinL.-P
In most cases, this is linked to how the medication affects digestion and appetite rather than a harmful reaction, and it is usually mild and temporary
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