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Participants were randomized to receive either once weekly subcutaneous cagrilintide plus semaglutide at either 2.4 mg (n=90) or 1.0 mg each (n=93), or a dose-matched placebo (pooled

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Clinical Evidence: Why GLP-1 Works for Weight Loss and Diabetes The landmark SUSTAIN and SELECT trials demonstrated that GLP-1 agonists reduce body weight by 5 to 22 percent depending on the medication, dose, and baseline characteristics