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Human data: two healthy adults tolerated 20 mg IV without adverse events (Lee & Burgess, 2025) the only formal human safety data
These include- Aged over 75 Decreased stomach acid Frequent use of antacids Autoimmune conditions affecting the stomach High doses of folic acid Stomach surgery Prolonged use of metformin Adoption of a vegan or vegetarian diet Excessive alcohol consumption How Does Vitamin B12 Benefit Your Body
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