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FIGURE 9 Summary and conclusions: Glutathione and early (premature) inflammaging Chronic inflammatory diseases especially those compromising the lower respiratory system (chronic obstructive pulmonary disease, lower respiratory infections, cystic fibrosis, idiopathic pulmonary fibrosis, acute respiratory distress syndrome), diseases compromising the cardiovascular system (atherosclerosis, ischemic heart disease, stroke, and others), many other systemic inflammatory diseases like diabetes (274, 275)
* and / or its thiol derivatives Die Glutathion-Reduktase, ein Flavoprotein, das die Funktion des Elektronenbertrgers erfllt, stellt in allen menschlichen Zellen ein Konzentrationsverhltnis von (G-SH) zu (G-S-S-G) von etwa 400 : 1 ein
Psoriasis is a skin condition characterized by itchy, scaly patches on the skin
According to the working model, these cysteine residues may undergo chemical modification/remodeling including trisulfide bond formation and/or related reactions, resulting in a regional (minor, but effective) structural alteration that enhances c-met binding and the nitration resistance of Y198-HGF
PMID 15717864
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