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Among them, PD-L1 shows a wide range of expression on hematopoietic cells and non-hematopoietic cells, while PD-L2 is only expressed on APCs (antigen presenting cells) (Moy et al., 2017)
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Perkovic V, Jardine MJ, Neal B, Bompoint S, Heerspink HJL, Charytan DM, Edwards R, Agarwal R, Bakris G, Bull S, Cannon CP, Capuano G, Chu P-L, de Zeeuw D, Greene T, Levin A, Pollock C, Wheeler DC, Yavin Y, Zhang H, Zinman B, Meininger G, Brenner BM, Mahaffey KW
Creatine is generally well-tolerated and safe to use alongside GLP-1s
Clinical trials and patient outcomes support this claim, and the FDA has approved semaglutide for this purpose
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