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& El-Sayed, M
A 2022 review and meta-analysis found that doses as low as 50mg per day could have a reductive effect on cholesterol,37 and we know from other research that high cholesterol can lead to liver fibrosis.38 The same 2022 review found that at least 500mg of artichoke leaf per day provided the greatest impact on liver markers like ALT and AST.37 However, certain users should be aware of serious side effects when ingesting artichoke
The trial in people with T2D included 281 participants (mean age 56 years, 56% women, mean BMI 35.0 kg/m 2 , mean HbA1c 8.3%) treated with lifestyle only and/or metformin, with similar intervention arms to the obesity trial, albeit retatrutide 0.5 mg rather than 1 mg, and dulaglutide 1.5 mg was an additional comparator [46]
So, if you remember anything from this section, let it be this
Mitsui, Y., Schmelzer, J
