These drugs have several additional effects, including a broad spectrum of metabolic effects such as anti-inflammatory properties, oxidative stress attenuation, or a positive impact on glucose and lipid metabolism
Success rates vary by agency, topic, and phase, but most agencies fund somewhere between 10% and 25% of Phase I proposals
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Less common but more serious reactions have also been reported, including pancreatitis, gallbladder issues, kidney problems, and severe gastrointestinal symptoms
