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When GHK-Cu application stops, copper supplementation ceases potentially reducing these enzymatic activities if dietary copper intake and natural skin copper levels prove insufficient for maintaining treatment-level effects

NSAID medications like ibuprofen and naproxen may counteract some of the peptides beneficial effects, though research also shows BPC-157 can protect against NSAID-induced gastrointestinal damage

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2023 Jul 24;16(7):1052