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The medication needs time to build up, and the starting dose is intentionally conservative
We do not yet have clear answers on: Long-term safety Optimal dosing strategies Metabolic interactions Effects on weight loss outcomes Some patients who stop GLP-1 treatment may see lost weight return over time
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Although these individual pathways have been traditionally well-defined, how NADPH-dependent inflammatory and anti-inflammatory processes co-regulate each other to fine-tune an optimized inflammatory response is not well understood
So from that angle, we learned that the body always adapts the weight gain but never adapts the weight loss
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