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This finding highlights the importance of considering sex differences and hormonal status in preclinical evaluations to enhance clinical translation

Code numbers were given to the subjects and written on folded papers for randomized selection

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As our understanding of the heterogenous factors driving OSA advances, novel therapies targeting specific physiological traitssuch as arousal threshold, ventilatory instability, and upper airway muscle responsivenessare being actively explored, with a promise to expand our therapeutic arsenal

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