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The STEP 1 trial (Wilding et al., The Lancet, 2021) showed an average weight loss of 14.9% over 68 weeks versus 2.4% in the placebo group a landmark result that established semaglutide as the benchmark for GLP-1 weight loss

METH is predominantly abused in its hydrochloride salt form, which appears as a colorless crystalline substance that is highly soluble in water and ethanol