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You may also have stretch marks, which are lines that can come up on your skin when your skin stretches and shrinks rapidly
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Clinical trials have shown promising results for Tirzepatide, with patients losing an average of 11 to 13.1% of their body weight over six months in a phase 2 trial, and even more encouraging results in phase 3 trials
For patients on levothyroxine or other thyroid medications , monitoring should be clinician-guided: Baseline assessment: TSH and free T4 before starting Mounjaro, if not recently checked Consider testing: If clinically meaningful changes occur (significant weight loss, new symptoms, or after substantial dose escalation) Ongoing monitoring: Follow usual annual monitoring when stable, in line with NICE NG145 guidance Post-weight loss: Consider additional testing once target weight is achieved and stabilised Significant weight loss can alter the volume of distribution and metabolism of thyroid hormones, potentially requiring dose adjustments
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