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Abstract GS01-03: Adding atezolizumab to adjuvant chemotherapy for stage II and III triple-negative breast cancer is unlikely to improve efficacy: interim analysis of the ALEXANDRA/IMpassion030 phase 3 trial

A post-mortem study examining brain tissue from individuals with mood disorders found lower expression of GLP-1 receptors in the prefrontal cortex and hippocampus compared to healthy controls

In pancreatic beta cells, GLP-1RA promotes the conversion of proinsulin to mature insulin by upregulating the expression of hormone converting enzymes PC1/3 and PC2, while reducing the proinsulin/insulin ratio and enhancing insulin biological activity

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Animals were placed in a stereotaxic apparatus and maintained in anesthesia with 2.5% isoflurane in 70/30% medical air/oxygen