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Long-term human safety data does not exist, which is the main caution
PMID: 30915550 | doi:10.1007/s00441-019-03016-8 Seiwerth S et al
Color changes from clear to yellow, amber, or any other tint suggest chemical degradation
The absence of established treatment protocols makes it difficult to determine optimal dosing regimens, treatment duration, and comprehensive monitoring requirements
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