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Among patients with type 2 diabetes, the risk of NAION was increased by 4.28 times, while in those using the drug for weight management, the risk surged by 7.64 times
Longer, well organized, double-blind RCTs with larger sample sizes in individuals with or without T2D are anticipated in order to investigate the safety, activity, and limitations of both drug categories to decrease OSA severity and improve cardiovascular outcomes
A couple of the most well-known are tirzepatide (Zepbound) and semaglutide (Wegovy)
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Neither produces the magnitude of weight loss seen with incretin peptides
