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Dehydration Nausea, reduced thirst cues, or eating less can make it easier to fall behind on fluids, which can contribute to fatigue and headaches
Flushing and Vascular Stress Both peptides can cause flushing and changes in circulation, creating discomfort or placing added stress on the vascular system
But that is the best cases
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No consistent increase in arrhythmias has been demonstrated in cardiovascular outcomes trials
For users considering combining semaglutide and tirzepatide , this is a clinical decision that requires direct supervision from a qualified provider
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