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The Numbers Behind Blood Pressure Reduction When researchers combine results from many studies, they find that GLP-1 medications lower systolic blood pressure (the top number) by: 2 to 6 mmHg on average when compared to placebo Semaglutide: about 3 to 5 mmHg reduction Liraglutide: about 2.5 to 3 mmHg reduction Tirzepatide: about 7 to 11 mmHg reduction (the most powerful) These numbers might seem small, but they matter
Compounded tirzepatide is not FDA-approved , but it is often prescribed when branded medications are in short supply or when a patient needs a more personalized dosage
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