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Of note, all the studies undertaken in the OCC included in this meta-analysis used 3 T MRS strength, whereas there was variation in MRS strength across the other brain regions (7 T was used for two MFC studies, with 3 T used for three MFC studies)
Further research into how GLP-1 receptors control VAT metabolism would also provide important insights into the influence of gut hormone-based therapies on weight changes
Importantly, liver transcriptomic analysis demonstrated that semaglutide reduced the expression of genes involved in hepatic steatosis, inflammation, and fibrosis, which was confirmed histologically for steatosis and inflammation, but not for fibrosis [33]
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