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The volume (2,402 complaints) is unusually high
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GI side effects like nausea amplify significantly when combined with alcohol
Neumiller: For SGLT2 inhibitors, it is important to educate people with type 1 diabetes about situations and factors that can increase their risk for experiencing DKA, such as acute illness, engaging in strenuous exercise, excessive alcohol intake, missing insulin doses, dramatic decreases in carbohydrate intake and insulin pump failure
In addition, GSSG retained in mitochondria during oxidative stress can lead to the S-gluthionylation of target proteins with mitochondrial dysfunction (20, 21)
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