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doi: 10.1146/annurev-physiol-021317-121332 94 GoyalRKGuoYMashimoH
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doi: 10.1016/j.brainres.2012.07.029 168 ParthsarathyVHolscherC
While short-term LC supplementation has demonstrated positive effects, including increased endurance, improved hepatic fat metabolism, and myocardial stability, evidence indicates that the prolonged supplementation may pose risks, particularly for individuals with pre-existing cardiovascular or renal conditions
The relative contributions of each receptor to overall efficacy and tolerability are under ongoing investigation
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