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Low GSH, neutrophil infiltration, myeloperoxidase activity and inflammation increase oxidative stress overwhelming the antioxidant defense, and hypochlorous acid mediated GSH oxidation and its attachment to proteins contribute to further GSH deficiency (114)
Green DR, Llambi F
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We investigated the effects of NAC both alone and in combination with IFN- and other cytokines, on endometriotic cell responses with a focus on ER stress induction, metabolic pathway alterations, and proliferation inhibition
Transcriptome signatures were clearly separated from NASH patients with cirrhosis (fibrosis stage 4), demonstrating perturbations in genes associated with extracellular matrix remodeling and the immune system
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