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Our results are clinically relevant and consistent with clinical reports that the secretory capacity of -cell was diminished in first-degree relatives of individuals with T2DM even before the onset of obesity and insulin resistance 32
In fact, it has been demonstrated that several molecules secreted by beta cells, such as insulin, zinc, and c-aminobutyric acid, inhibit the secretion of glucagon
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Clinical studies have shown that MDA levels in serum and plasma samples of MASLD patients are significantly higher than in healthy individuals [133]
These factors might decrease access due to the cost of these medications, particularly when paying out of pocket
