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Retatrutide, on the other hand, is a newer investigational agent described as a triple-agonist (targeting GLP-1, GIP, and glucagon receptors) and has demonstrated promising early data for greater weight reduction and fat-burning potential

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History of medullary thyroid carcinoma MEN2 syndrome Severe pancreatitis history Severe gastroparesis Pregnancy or breastfeeding A full medical evaluation is required before prescription