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Preserving its reduced state and supporting GSH levels may, therefore, promote healthy brain aging and enhance resilience to neurological disease

Such nonnative disulphide bonds are now known to form in proteins under normal physiological conditions (Jansens et al , 2002)

Figure 8 Calculation of the degree of oxidation ( OxD ) of both probes from the ratiometric imaging data presented in Figure 8 showed a low OxD of only 14% for GRX1-roGFP2-iL and a corresponding high OxD of 93% for GRX1-roGFP2 (Figure 9A)