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These are pathway-level variants: they do not predict how you will respond to semaglutide, but they map the biology a clinician is working with
It is being studied for its potential to improve glycemic control and assist in weight management in individuals with and without T2D, at a maximum dose of 12mg/weekly [11]
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J Clin Endocrinol Metab 86:12291234 Bi Y, Zhang B, Xu W et al (2014) Effects of exenatide, insulin, and pioglitazone on liver fat content and body fat distributions in drug-naive subjects with type 2 diabetes
So all of those changes conspire to put weight on
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