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2-AR also mediates cellular responses via Gai-induced generation of cGMP and intracellular elevation of Ca 2+

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Notably, liraglutide treatment significantly inhibited activated sodium-glucose co- transporter-2 (SGLT2) restored depressed insulin receptor substrate 1 (IRS1), and increased protein kinase G (PKG) levels

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6.2 Synergistic role of NAC with ATT Khameneh et al

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