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*Source: Chao AM, Tronieri JS, Amaro A, Wadden TA

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These tests typically screen for substances such as opioids, amphetamines, benzodiazepines, and cannabinoids, not GLP-1 receptor agonists like semaglutide

To generate sufficient quantities of ROS and RNS quickly, these cells require rapid flux through the PPP to produce sufficient amounts of NADPH to enable superoxide formation from oxygen by the action of NADPH oxidase (NOX), and nitric oxide (NO) formation from arginine by inducible nitric oxide synthase (iNOS) ( Figure 1A-2 )

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