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Clinical research has confirmed no effect on IGF-1 levels and no negative impact on carbohydrate metabolism

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Studies observing Nrf2 deficient mice have shown that they are at great risk of developing a wide variety of autoimmune disorders, including lupus, multiple sclerosis, hemolytic anemia, rheumatoid arthritis, and many others (24, 25, 26, 27, 28)

Science 339:122202 Wang C, Liu Q, Guo G, Huo WJ, Ma L, Zhang YL (2016) Effects of dietary supplementation of rumen protected folic acid on rumen fermentation, degradability and excretion of urinary purine derivatives in growing steers

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