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The Wegovy dosage schedule starts at a low dose and gradually increases to minimise the risk of side effects
Think of it as easing into cool water instead of jumping in
SURMOUNT-1 (Jastreboff 2022, NEJM) reported up to 20.9 percent average weight loss with tirzepatide versus 14.9 percent with semaglutide in STEP 1 (Wilding 2021, NEJM)
GLP-1 analogs are thought to impact the brains reward circuits, leading to fewer cravings and decreased use
As it stands, weight loss surgery is by far the most effective way to treat obesity today
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