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Diabetes, Obesity & Metabolism, 27 (5), 28102821
Clinical trials have demonstrated cardiovascular and renal protection, leading to additional approvals in high-risk populations
The MHRA approval is based on the OASIS 4 phase 3 clinical trial, which studied the 25mg semaglutide tablet in adults living with obesity, or overweight with at least one weight related condition, who did not have diabetes
However, both medications can cause gastrointestinal side effects, so take ibuprofen with food and use the lowest effective dose for the shortest duration
Ultra-processed diets cause excess calorie intake and weight gain: A controlled inpatient trial
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