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The FLOW trial, a double-blind, placebo-controlled study examining renal outcomes in patients with type 2 diabetes and chronic kidney disease, demonstrated that semaglutide reduced the progression of kidney disease by 24% compared to placebo

Side effects are rare but can include mild headache, lightheadedness, or temporary flushing

It also adds uncertainty without proving better long-term outcomes

Dosage adjustments : Using both therapies might require adjustments to dosage to optimize their effectiveness and minimize side effects

B% 11.70, 13.86, 13.98, 15.77, 12.42, 20.22, and 12.05, respectively) were identified in the kidney of control rats