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The lactam bridge between Asp and Lys constrains MT-2 into a beta-turn conformation that enhances potency and broadens melanocortin receptor activity compared to linear analogs
Wani MA, Haynes LD, Kim J, Bronson CL, Chaudhury C, Mohanty S, et al
Although data on semaglutide administration in pregnant women is sparse, there is some concern that it may cause fetal harm
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Acta 1533 : 4754 Bauer G (2000) Reactive oxygen and nitrogen species: efficient, selective, and interactive signals during intercellular induction of apoptosis
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