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These medications have extraordinary potential
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Mechanistically, since SGLT2 is not expressed in cardiomyocytes, SGLT2 inhibitors exert their cardioprotective effects indirectly by targeting noncardiomyocytes, such as by inducing diuresis, modulating neurohormonal activation, and improving metabolism, rather than through direct actions on cardiomyocytes
Both cause slurred speech, poor coordination, confusion, and drowsiness
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