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The GLP-1 derived from intestinal L cells may also communicate with the CNS through GLP-1Rs located in fibers innervating the portal vein or in the vagus nerve
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Institute for Health Metrics and Evaluation, GBD Results, Accessed 24 November 2024
Notably, Akkermansia muciniphila , often linked to improved insulin sensitivity and reduced inflammation, has shown increased abundance following semaglutide administration, supporting its potential therapeutic relevance [83]
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